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Genome editing refers to a set of modern biotechnology tools used by scientists to make precise changes in an organism’s DNA, also known as the genome. Genome editing is increasingly being used to generate new crop varieties that can be used in food and/or animal feed. To read more about genome editing, refer to Safety of Genome Edited Crops.
© 2026 Singapore Food Agency
Last Updated 28 May 2026
Both genome edited (GEd) and genetically modified (GM) crops have had their DNA changed using tools from modern biotechnology. However, GEd and GM crops differ in how they are made:
Genome editing tools allow crop developers to make precise changes in an organism’s DNA. On the one hand, these changes can be small without introducing foreign DNA. The resulting GEd crop is equivalent to crop varieties found naturally or bred using conventional breeding techniques. On the other hand, genome editing can introduce foreign DNA into a crop – the resulting crop is equivalent to a GM crop.
Genetic modification tools insert foreign DNA into a crop, which confers new desirable traits. The resulting GM crop could not have been found naturally or bred using conventional breeding techniques.
Ensuring the safety of food innovations is SFA's principal consideration. SFA has therefore developed a science-based and risk-proportionate regulatory framework for genome edited (GEd) crops used in food and/or animal feed.
Under this framework, GEd crops that are equivalent to conventionally bred crops are not required to undergo a pre-market safety assessment. Nonetheless, crop developers are encouraged to notify SFA prior to the sale of such GEd crops.
GEd crops that are equivalent to genetically modified (GM) crops are required to undergo a pre-market safety assessment and approval process before they can be used in food.
SFA will continue to monitor all GM and GEd crops on the market to ensure their safety. SFA will also continue to work with different stakeholders, including the industry and members of the public, in implementing this regulatory framework to ensure the safe use of GEd crops in food and feed.
SFA classifies genome edited (GEd) crops intended for use as food and animal feed as follows:
GEd crops without foreign DNA are crops that could have been generated via conventional breeding. If you are developing a GEd crop without foreign DNA, you are encouraged to notify SFA by submitting an Information Checklist.
GEd crops that contain foreign DNA are crops that could not have been generated via conventional breeding. SFA requires such crops to undergo the pre-market safety assessment process for GMOs.
| Type of GEd crops | Guidelines for crop developers |
|---|---|
| GEd crops without foreign DNA | You are encouraged to notify SFA by submitting an Information Checklist. SFA will verify that the developer has performed the necessary steps and checks that the crop is equivalent to conventionally bred crops.
Please refer to the Guidance on regulatory framework for genome edited crops for use as food and feed for information on the Notification process.
When the GEd crop is verified by SFA to not contain foreign DNA, the completed Notification will be in the List of genome edited (GEd) crops that have completed Pathway A* under SFA’s regulatory framework for GEd crops. |
| GEd crops with foreign DNA | SFA requires such crops to undergo the pre-market safety assessment process for GMOs. You may refer to Conditions related to use of genetically modified crops in food. |
You may also read more here:
Information on gene editing by the Food and Agriculture Organization (FAO) of the United Nations
For more information
You can contact us via the SFA Online Feedback Form.
